2021 Early Career Investigator Program Winners

2021 Early Career Investigator Program – Travel Awards Winners:

Arjun Bhattacharya, University of California at Los Angeles | Genome-Wide Genetic Control of Fetal Placental Genomics Informs the Development of Health, Disease, and Neuropsychiatric Disorders

Christiaan de Leeuw, Vrije Universiteit | Reconsidering the Validity of Transcriptome-Wide Association Studies

Giuseppe Fanelli, University of Bologna | Insulinopathies of the Brain? Genetic Overlap Between Somatic Insulin-Related and Neuropsychiatric Disorders 

Suhas Ganesh, Yale University | Polygenic Risk Score for Cannabis Use Disorder Predicts Acute Intoxicating Effects and Cognitive Deficits Induced by Delta-9-Tetrahydrocannabinol: A Pilot Study

Emily Hartwell, University of Pennsylvania | Differences in Phenotypic Associations of Genetic Liability for Substance Use by Ancestry and Sex

Bharath Holla, National Institute of Mental Health and Neurosciences (NIMHANS), India | Gene-Environment Interaction and Brain Networks in the Pathophysiology of Externalizing Behaviors and Substance Use Risk

Farhana Islam, University of Toronto | Effects of CYP2C19 and CYP2D6 Gene Variants on Escitalopram and Aripiprazole Treatment Outcome and Serum Levels: Results from the Can-Bind 1 Study

Patricia Kipkemoi, KEMRI-Wellcome Trust | Genetic Characterization of Neurodevelopmental Disorders in African Populations: The Neurodev Trio Pilot

Lindsay Melhuish Beaupre, Center for Addiction and Mental Health | Bigenomic Association Study of Accelerometer-Derived and self-Reported Sleep Properties Across UK Biobank Participants With Lifetime Major Depressive Disorder

 

Gita Pathak, Yale School of Medicine | Genetically Regulated Multi-Omics Investigation of Prefrontal Cortex for Symptom Clusters of Posttraumatic Stress Disorder in US Veteran  Population

William Reay, University of Newcastle | Integration of Transcriptomic and Proteomic Data to Refine Polygenic-Risk Informed Drug Repurposing Candidates for Psychosis

Xueyi Shen, University of Edinburgh | Dna Methylome-Wide Association Study of Polygenic Risk Scores for Depression Implicating Antigen Processing and Immune Responses

Lea Sirignano, Central Institute of Mental Health, University Medical Center Mannheim/University of Heidelberg | Longitudinal Methylome-Wide Analysis in Patients Undergoing Electroconvulsive Therapy

Nora I. Strom, Humboldt Universität zu Berlin | Genome-Wide Association Study of Obsessive-Compulsive Symptoms and Hoarding Symptoms in the General Population

Jackson Thorp, QIMR Berghofer Medical Research Institute | Symptom-Level Genetic Modelling of Depression and Anxiety

Dennis van der Meer, Norwegian Centre for Mental Disorders Research, Oslo University Hospital and University of Oslo | Improving the Discovery of Genetic Variants with Distributed Effects on Brain Morphology and Psychiatric Traits

Ruyue Zhang, Karolinska Institutet |  Novel Disease Associations With Schizophrenia Genetic Risk Revealed in ~400,000 Uk Biobank Participants

 

 

 

2021 Early Career Investigator Program – Poster Presentation Winners
Djenifer B. KappelCardiff University | Schizophrenia Genetic Liability and Clozapine Doses: A First Step Towards the Polygenic Analysis of Response to Antipsychotic Treatment

Yingjie ShiRadboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour | Polygenic Models of Comorbidity and Pleiotropy in Psychiatry in a Highly Comorbid Cohort

Elleke TissinkCenter for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam | The Genetic Architecture of Cerebellar Volume

2021 Early Career Investigator Program – Poster Presentation Finalists
Anthony Abrantes, UNC-Chapel Hill | Gene Expression Changes following Chronic Antipsychotic Exposure in Single Cells From Mouse Striatum

Mohammad Ahangari, Virginia Commonwealth University | Investigating the Source of Elevated Bipolar and Major Depressive Disorder Polygenic Risks in Multiplex Schizophrenia Families

Isabell Brikell, Karolinska Institutet | Associations and Interactions of ADHD Polygenic Liability With Pre-and Perinatal, Somatic, and Psychosocial Risk-Factors in the Development of ADHD – A Nationwide Study

Anthony Fischer, Washington University School of Medicine | Massively Parallel Analysis of Autism Spectrum Disorder Non-Coding Variants

Isabelle Foote, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK | A Multivariate Genome-Wide Association Study of Modifiable Risk for Alzheimer’s Disease: 269 Loci Associated With Brain Health

 

Thi Thuy Dung Nguyen, Karolinska Institutet | Genetic Contribution to Major Depressive Disorder Heterogeneity- Family Designs Using Swedish National Registers

Georgia Panagiotaropoulou, Charite University Hospital | Pathway-Based Polygenic Risk Scores Using Machine Learning Classification Schemes: Application to Bipolar Disorder

Ethan Poweleit, University of Cincinnati | CYP2C19 Metabolizer Phenotype Predicts Sertraline Pharmacokinetics in Children and Adolescents

Laura Vilar-Ribó, Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d’Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain | Shared Genetic Architecture and Causal Relationships Between Attention-Deficit and Hyperactivity Disorder and Lifespan

2021 Early Career Investigator Program – Oral Presentation Winners
Christiaan de LeeuwVrije Universiteit | Reconsidering the Validity of Transcriptome-Wide Association Studies

Samuel PowellIcahn School of Medicine at Mount Sinai | Genetic Risk Architecture of Schizophrenia and Three-Dimensional Chromatin Dynamics Across Neurotransmitter Systems

Cindy WenUniverstiy of California Los Angeles (UCLA) | Large-Scale, Multi-Ethnic Resource of Gene, Isoform, and Splicing Regulation in the Developing Human Brain

2021 Early Career Investigator Program – Oral Presentation Finalists
Siwei ChenMassachusetts General Hospital | Ultra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 32K Individuals

Marieke Klein, UC San Diego | Analysis of Genomic Copy Number Variation and Their Interaction With Polygenic Risk Scores Across Psychiatric Disorders

Xiangrui Meng, University College London | Genome-Wide Association Study of Depression in Individuals With African Ancestry Identifies Two Novel Genetic Associations

Rebecca Mahoney, Centre for Neuroimaging, Cognition and Genomics, Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland |  Using Cellular Deconvolution to Investigate Cell Subtype Proportions in Cortical Gene Expression Data in Schizophrenia

Daniel Roelfs, NORMENT, University of Oslo | Shared Genetic Determinants Between the Brain Functional Connectome and Psychiatric Disorders