2021 Early Career Investigator Program

2021 Early Career Investigator Program – Travel Awards Winners:

Arjun Bhattacharya, University of California at Los Angeles
Genome-Wide Genetic Control of Fetal Placental Genomics Informs the Development of Health, Disease, and Neuropsychiatric Disorders
Christiaan de Leeuw, Vrije Universiteit
Reconsidering the Validity of Transcriptome-Wide Association Studies
Giuseppe Fanelli, University of Bologna
Insulinopathies of the Brain? Genetic Overlap Between Somatic Insulin-Related and Neuropsychiatric Disorders
Suhas Ganesh, Yale University
Polygenic Risk Score for Cannabis Use Disorder Predicts Acute Intoxicating Effects and Cognitive Deficits Induced by Delta-9-Tetrahydrocannabinol: A Pilot Study
Emily Hartwell, University of Pennsylvania
Differences in Phenotypic Associations of Genetic Liability for Substance Use by Ancestry and Sex
Bharath Holla, National Institute of Mental Health and Neurosciences (NIMHANS), India
Gene-Environment Interaction and Brain Networks in the Pathophysiology of Externalizing Behaviors and Substance Use Risk
Farhana Islam, University of Toronto
Effects of CYP2C19 and CYP2D6 Gene Variants on Escitalopram and Aripiprazole Treatment Outcome and Serum Levels: Results from the Can-Bind 1 Study
Patricia Kipkemoi, KEMRI-Wellcome Trust
Genetic Characterization of Neurodevelopmental Disorders in African Populations: The Neurodev Trio Pilot
Lindsay Melhuish Beaupre, Center for Addiction and Mental Health
Bigenomic Association Study of Accelerometer-Derived and self-Reported Sleep Properties Across UK Biobank Participants With Lifetime Major Depressive Disorder
Gita Pathak, Yale School of Medicine
Genetically Regulated Multi-Omics Investigation of Prefrontal Cortex for Symptom Clusters of Posttraumatic Stress Disorder in US Veteran Population
William Reay, University of Newcastle
Integration of Transcriptomic and Proteomic Data to Refine Polygenic-Risk Informed Drug Repurposing Candidates for Psychosis
Xueyi Shen, University of Edinburgh
Dna Methylome-Wide Association Study of Polygenic Risk Scores for Depression Implicating Antigen Processing and Immune Responses
Lea Sirignano, Central Institute of Mental Health, University Medical Center Mannheim/University of Heidelberg
Longitudinal Methylome-Wide Analysis in Patients Undergoing Electroconvulsive Therapy
Nora I. Strom, Humboldt Universität zu Berlin
Genome-Wide Association Study of Obsessive-Compulsive Symptoms and Hoarding Symptoms in the General Population
Jackson Thorp, QIMR Berghofer Medical Research Institute
Symptom-Level Genetic Modelling of Depression and Anxiety
Dennis van der Meer, Norwegian Centre for Mental Disorders Research, Oslo University Hospital and University of Oslo
Improving the Discovery of Genetic Variants with Distributed Effects on Brain Morphology and Psychiatric Traits
Ruyue Zhang, Karolinska Institutet
Novel Disease Associations With Schizophrenia Genetic Risk Revealed in ~400,000 Uk Biobank Participants

2021 Early Career Investigator Program – Poster Presentation Finalists:
Anthony Abrantes, UNC-Chapel Hill
Gene Expression Changes following Chronic Antipsychotic Exposure in Single Cells From Mouse Striatum
Mohammad Ahangari, Virginia Commonwealth University
Investigating the Source of Elevated Bipolar and Major Depressive Disorder Polygenic Risks in Multiplex Schizophrenia Families
Isabell Brikell, Karolinska Institutet
Associations and Interactions of ADHD Polygenic Liability With Pre-and Perinatal, Somatic, and Psychosocial Risk-Factors in the Development of ADHD – A Nationwide Study
Anthony Fischer, Washington University School of Medicine
Massively Parallel Analysis of Autism Spectrum Disorder Non-Coding Variants
Isabelle Foote, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK
A Multivariate Genome-Wide Association Study of Modifiable Risk for Alzheimer’s Disease: 269 Loci Associated With Brain Health
Djenifer B. Kappel, Cardiff University
Schizophrenia Genetic Liability and Clozapine Doses: A First Step Towards the Polygenic Analysis of Response to Antipsychotic Treatment
Thi Thuy Dung Nguyen, Karolinska Institutet
Genetic Contribution to Major Depressive Disorder Heterogeneity- Family Designs Using Swedish National Registers
Georgia Panagiotaropoulou, Charite University Hospital
Pathway-Based Polygenic Risk Scores Using Machine Learning Classification Schemes: Application to Bipolar Disorder
Ethan Poweleit, University of Cincinnati
CYP2C19 Metabolizer Phenotype Predicts Sertraline Pharmacokinetics in Children and Adolescents
Yingjie Shi, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour
Polygenic Models of Comorbidity and Pleiotropy in Psychiatry in a Highly Comorbid Cohort
Dominic Sykes, University of Edinburgh
Using Neural Networks to Create a Polygenic Risk Score of Major Depressive Disorder
Elleke Tissink, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam
The Genetic Architecture of Cerebellar Volume
Laura Vilar-Ribó, Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d’Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Shared Genetic Architecture and Causal Relationships Between Attention-Deficit and Hyperactivity Disorder and Lifespan

2021 Early Career Investigator Program – Oral Presentation Finalists:
Siwei Chen, Massachusetts General Hospital
Ultra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 32K Individuals
Christiaan de Leeuw, Vrije Universiteit
Reconsidering the Validity of Transcriptome-Wide Association Studies
Sherif Gerges, Broad Institute of Harvard & MIT.
Single-Cell RNA-Sequencing of Human Brain Regions Identifies Cell Types and States Relevant to Disease
Marieke Klein, UC San Diego
Analysis of Genomic Copy Number Variation and Their Interaction With Polygenic Risk Scores Across Psychiatric Disorders
Xiangrui Meng, University College London
Genome-Wide Association Study of Depression in Individuals With African Ancestry Identifies Two Novel Genetic Associations
Rebecca Mahoney, Centre for Neuroimaging, Cognition and Genomics, Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland
Using Cellular Deconvolution to Investigate Cell Subtype Proportions in Cortical Gene Expression Data in Schizophrenia
Samuel Powell, Icahn School of Medicine at Mount Sinai
Genetic Risk Architecture of Schizophrenia and Three-Dimensional Chromatin Dynamics Across Neurotransmitter Systems
Daniel Roelfs, NORMENT, University of Oslo
Shared Genetic Determinants Between the Brain Functional Connectome and Psychiatric Disorders
Cindy Wen, UCLA
Large-Scale, Multi-Ethnic Resource of Gene, Isoform, and Splicing Regulation in the Developing Human Brain